Neuroflex , the only flexible Type 1 Collagen Conduit, is designed to create a protective environment for axonal growth across a nerve gap that is 2.5 cm or less. Neuroflex maintains all of the characteristics of Stryker’s first nerve repair product, NeuroMatrix, including being fully resorbable and semi-permeable, but with the potential benefit of being kink-resistant up to 60° ^1,2. Like NeuroMatrix, Neuroflex allows for a tensionless repair and comes in a variety of sizes. Neuroflex is manufactured by Collagen Matrix, Inc. in Franklin Lakes, NJ.

• Clinically effective⁷.
• Has the potential to allow a tensionless repair.
• Eliminates donor site morbidity associated with autografts⁵.
• Conveniently available off-the-shelf at the time of surgery.
• Available in six standard sizes for accurate size matching.
• No second surgery required to harvest autograft.
• Processed to promote non-inflammatory and resorbability ^1,3,5
• Helps to improve flexibility over standard collagen conduits^1,8.

Stryker Corporation or its divisions or other corporate affiliated entities own, use or have applied for the following trademark(s) or service mark(s):Neuroflex, NeuroMatrix . All other trademarks are trademarks of their respective owners or holders.

References

1. Data on file at Collagen Matrix, Inc.
2. Weber RA, Breidenbach WC, Brown RE, Jabaley ME, Mass DP. A Randomized Prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans. Plast Reconstr Surg 2000 Oct. 106(5): 1036-45;
discussion 1046-8.
3. Li ST, Rodkey WG, Yuen D, Hansen P, Steadman JR. Type 1 Collagen-Based Template for Meniscus Regeneration. Tissue Engineering and Biodegradable Equivalents. Scientific and Clinical Applications. 2002 pp 237-266.
4. Taras JS, Nanavati V, Steelman P. Nerve Conduits. J Hand Therapy. 2005 Apr-Jun; 18(2): 191-7. Review.
5. Trumble TE, Parisi D, Archibald S, Allan CH. Synthetic Nerve Conduits. Pp 121-128. Peripheral Nerve Surgery. Practical Applications in the Upper Extremity. Slutsky and Hentz. Elsevier 2006.
6. Lundborg G. Dahlin LB, Danielson N, Nachemson AK. Tissue specificity in nerve regernation. Scand J Plast Reconstr Surg. 1986; 20:279-83.
7. Mackinnon SE, Dellon AL, Lundborg G, Hudson AR, Hunter DA. A study of neurotropism in a primate model. J Hand Surgery [Am]. 1986; 11:888-94.
8. Li ST, Yuen D: U.S. Patent #6,716,225, Implant Devices for Nerve Repair, 2004.

The literature below has been developed to provide healthcare professionals with general product information.
Please note: not all products are available in all countries. For product availability or any further information, please contact your local Stryker representative.

	Neuroflex Operative Technique		190 kb
	Neuroflex Flyer		80 kb
	Neuroflex Inventory Control Sheet		65 kb